Monday 31 October 2011

World population hits 7 billion on Oct. 31, or thereabouts

It took only a dozen years for humanity to add another billion people to the planet, reaching the milestone of 7 billion Monday ? give or take a few months.

Demographers at the United Nations Population Division set Oct. 31, 2011, as the "symbolic" date for hitting 7 billion, while acknowledging that it's impossible to know for sure the specific time or day. Using slightly different calculations, the U.S. Census Bureau estimates the 7-billion threshold will not be reached until March.

Under any methodology, demographers agree that humanity remains on a steep growth curve, which is likely to keep climbing through the rest of this century. The U.N.'s best estimate is that population will march past 9.3 billion by 2050 and exceed 10.1 billion by the end of the century. It could be far more, if birthrates do not continue to drop as they have in the last half-century.

Nearly all the projected growth this century is expected to occur in developing countries in Asia, Africa and Latin America, while the combined populations in Europe, North America and other wealthy industrialized nations will remain relatively flat. Some countries, such as Germany, Russia and Japan, are poised to edge downward, their loss made up mostly by ongoing growth in the United States, which is bolstered by waves of immigrants.

The buildup to Monday's milestone has briefly turned up the flame on long-simmering debates about growth on a finite planet: Whether a growing population or growing consumption remains the biggest environmental challenge, how best to help lift a billion people out of poverty and misery, whether governments should provide contraception for those who cannot afford it.

The new leader of the United Nations Population Fund, Dr. Babatunde Osotimehin, a Nigerian obstetrician-gynecologist, stepped gingerly into the fray. His agency remains a favorite punching bag of antiabortion activists in the United States for its role in supporting family planning clinics in developing countries.

"Instead of asking questions like, 'Are we too many?' we should instead be asking, 'What can I do to make our world better?' " wrote Osotimehin in the annual State of the World Population report. The report chronicles disparities between rich nations and poor ones. Poor countries continue to have low education levels and startlingly high rates of teenage pregnancy and maternal and child deaths due to complications from childbirth.

"In many parts of the developing world, where population growth is outpacing economic growth, the need for reproductive health services, especially family planning, remains great," Osotimehin concluded.

Some have used the occasion to celebrate the unrivaled success of the human species. Population grows when births exceed deaths. The 7-billion mark was reached because people are living longer and the number of infant deaths has dropped, because of a more secure food supply and because of advances in sanitation and medicine.

U.N. Secretary-General Ban Ki-moon will hold a news conference Monday to mark the date and talk about challenges ahead, particularly how to reduce poverty, invest in the world's 1.8 billion youth and help countries develop in a sustainable way.

In 1999, his predecessor, Kofi Annan, designated a boy born to refugee parents in Sarajevo, Bosnia-Herzegovina, as Baby 6 Billion. He had been plucked from the hundreds of thousands of babies born that day to put a face on global population growth. Adnan Mevic, now 12, has become something of a celebrity.

None of the estimated 382,000 babies born Monday will have such an honor.

There is no word yet on how the United Nations will handle the next milestone, when the globe's population hits 8 billion ? about 14 years from now.

ken.weiss@latimes.com

Source: http://feeds.latimes.com/~r/latimes/news/science/~3/ffbra0jhWCI/la-fg-seven-billionth-baby-20111031,0,4893410.story

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Sunday 30 October 2011

Expert: Jackson likely gave self fatal propofol shot (Reuters)

LOS ANGELES (Reuters) ? Michael Jackson likely injected himself with a fatal dose of the anesthetic propofol after popping an extra eight sedatives without his doctor's knowledge, a Los Angeles court heard on Friday.

Dr. Paul White, the last defense witness in the involuntary manslaughter trial of the singer's physician, Dr. Conrad Murray, said that self-administration was the most likely scenario to explain levels of propofol and lorazepam found in Jackson's system after his death on June 25, 2009.

White said that based on the amount of propofol found in Jackson's urine, he believed the pop star gave himself a further injection of propofol about one hour after Murray has admitted injecting the 50 year-old singer with a relatively small 25 milligram dose of the drug as a sleep aid.

"With the administration of the additional 25 milligrams that we're speculating was self-injected by Mr. Jackson, the level increases rapidly and at the time of death would be almost identical to the level found in the urine at autopsy," White told jurors.

Using a mathematical model, White also said Jackson could have swallowed eight lorazepam tablets earlier in the night as he struggled with sleeplessness, bringing the amount of the sedative found in his blood to that seen at autopsy.

"The combination effect is potentially profound," White said of the two drugs.

Authorities have ruled Jackson died of an overdose of propofol, with lorazepam playing a contributing role.

A rival expert testified for the prosecution last week that he believed Jackson died after Murray left him on an intravenous drip of propofol for a number of hours.

But White said there was no physical evidence at the scene to support the prosecution scenario. It also did not reconcile with Murray's statements about the amount of drugs he gave Jackson that night, White said.

Prosecution experts will cross examine White on Monday as the five-week trial enters its closing stages.

White on Friday questioned the mathematical modeling prepared by prosecution expert Dr. Steven Shafer to support the intravenous propofol drip theory.

In order to reach the blood level of propofol found at autopsy, Jackson would have had to stop breathing right as the last drops fell from a 1,000 milligram bottle of propofol given with an IV drip, White said.

White called Shafer's hypothesis an "incredible coincidence of circumstances."

Murray denies involuntary manslaughter but could face up to four years prison if convicted. His attorneys said earlier this week he will not testify in his own defense.

Murray told police he had been trying to wean Jackson off his dependence on propofol. But he claimed the singer begged him for the drug the day he died.

Prosecution witnesses have also testified that Murray delayed calling emergency services, failed to tell ambulance and hospital staff about the propofol, and say he should never have been giving Jackson the drug for insomnia at all.

(Editing by Jill Serjeant and Eric Walsh)

Source: http://us.rd.yahoo.com/dailynews/rss/celebrity/*http%3A//news.yahoo.com/s/nm/20111028/en_nm/us_michaeljackson

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Step toward unraveling Alzheimer's disease

ScienceDaily (Oct. 27, 2011) ? Scientists outline new methods for better understanding links between specific proteins and the risks associated with Alzheimer's disease in an article co-authored by University of Alabama researchers and publishing in Science Express.

In experiments using a series of model organisms, including yeast, microscopic roundworms and rats, the researchers show how basic mechanisms inside cells are disrupted when a specific human protein, known as the amyloid beta peptide, fails to properly fold. This study also shows the role a second protein, referred to by the scientists as PICALM, can play in modifying the problem.

"By using these yeast models, in combination with worms, we really are hopeful of finding a way by which we can understand and maybe combat Alzheimer's disease more rapidly," said Dr. Guy Caldwell, professor of biological sciences at The University of Alabama and one of three UA-authors on the Science article.

The research involved scientists from several universities and research institutes, including the Whitehead Institute and Massachusetts Institute of Technology, where the lead author, Dr. Sebastian Treusch, is affiliated. Treusch works in the lab of Dr. Susan Lindquist, a renowned expert in cell biology and collaborator with Caldwell on a grant from the Howard Hughes Medical Institute that funded part of this research.

While the repeated misfoldings of amyloid beta peptides within the human brain were previously known to trigger the death of neurons, resulting in Alzheimer's, Caldwell says the underlying mechanisms of toxicity weren't as well understood.

Properly functioning cells must efficiently deliver proteins and chemicals to other parts of the cell, Caldwell said. This research shows how the amyloid beta peptide interrupts a specific cellular pathway called endocytosis, preventing the delivery of other needed proteins to other parts of the cell.

"Understanding what is going wrong inside a cell, or what pathways or proteins might be directly linked to the mechanisms that are involved in Alzheimer's, is really a much more fruitful strategy for drug development."

Information drawn from the brains of deceased Alzheimer's patients, who previously donated their bodies to science, was also significant in the effort, Caldwell said.

Rapid advances in DNA sequencing methods and human genetic population studies are generating an overwhelming number of leads for researchers; those genetic studies, taken in combination with advantageous attributes of simple organisms, can reveal basic functions of genes and proteins and can be an insightful combination, Caldwell says.

"What this paper shows is that simple systems, like yeast and worms, can be engineered to discern mechanisms that might be associated with complex human diseases, and, by that, we may accelerate the path of discovery for advancing therapeutics for those diseases."

UA's lead author is Dr. Shusei Hamamichi, a former post-doctoral researcher in the Caldwell lab who earned his doctorate at UA while working alongside Caldwell and Dr. Kim Caldwell, also a co-author of the paper and an associate professor of biological sciences at UA.

In the paper's conclusion, the researchers describe the potential significance of the development in light of the challenges faced in understanding and treating Alzheimer's disease.

"The treatments available for AD are few and their efficacy limited," the scientists wrote. "Determining how best to rescue neuronal function in the context of the whole brain is a problem of staggering proportions."

"On a personal level," Caldwell said, "so many of us have been affected by family or loved ones who have suffered from Alzheimer's. It's a great privilege for us to be able to contribute to the respective avenues of our understanding of the disease. It's a devastating disorder. The societal cost of Alzheimer's disease is tremendous."

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The above story is reprinted from materials provided by University of Alabama in Tuscaloosa.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Sebastian Treusch, Shusei Hamamichi, Jessica L. Goodman, Kent E. S. Matlack, Chee Yeun Chung, Valeriya Baru, Joshua M. Shulman, Antonio Parrado, Brooke J. Bevis, Julie S. Valastyan, Haesun Han, Malin Lindhagen-Persson, Eric M. Reiman, Denis A. Evans, David A. Bennett, Anders Olofsson, Philip L. Dejager, Rudolph E. Tanzi, Kim A. Caldwell, Guy A. Caldwell, Susan Lindquist. Functional Links Between A? Toxicity, Endocytic Trafficking, and Alzheimer?s Disease Risk Factors in Yeast. Science, 2011; DOI: 10.1126/science.1213210

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2011/10/111027145851.htm

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Saturday 29 October 2011

How Long All Those Halloween Candy Bars Will Last [Halloween]

How Long All Those Halloween Candy Bars Will LastIf you have trick-or-treaters in the house or tend to over-prepare for visiting ones, chances are you'll have some candy bars left over next week. How long are they good for? Slate tackles this question and more about old chocolate.

Chocolate bars usually have expiration dates on them, but we know that food expiration labels are more suggestions about quality than hard-and-fast rules about safety. When it comes to candy bars, the chocolate may stay fresh for about 12 months and pure chocolate can last for two years, according to Slate (so you might be able to save that candy for next Halloween!). Ingredients like nuts or peanut butter can make a candy bar go bad faster, however, with the quality expiration time of about a year for nuts.

Learn more about chocolate bar freshness (like how to deal with those harmless white spots that show up on old chocolate) at the explainer article below. Photo by Calgary Reviews.

No One Better Lay a Finger on This Butterfinger | Slate


You can follow or contact Melanie Pinola, the author of this post, on Twitter or Google+.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/I8WSJCidTN0/how-long-all-those-halloween-candy-bars-will-last

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'Plastic Ocean' Book Chronicles A Quest To Save The Seas (PHOTOS)

Captain Charles Moore had an unexpected discovery in 1997. Traveling between Hawaii and California, Moore is said to be the first to document what became known as the Great Pacific Garbage Patch.

Writing in his new book "Plastic Ocean," Moore says he didn't know he would "gain a surprising amount of notoriety as the 'discoverer' of the Great Pacific Garbage Patch." Since then, Moore has spent time learning about the Pacific plastic dump and the impact that so much plastic has had on fragile ocean ecosystems.

While one scientist has argued that the Great Pacific Garbage Patch isn't "twice the size of Texas" as others have suggested, the amount of plastic in the ocean is still an important concern.

Moore contends that the term "garbage patch" is misleading and that it is more like "plastic soup."

Speaking about the plastic in the Pacific, Moore said, "It's something that's new. It took a long time for us to believe that this change we're noticing in our climate was due to human activity; very hard to believe. This is an easier sell because it's visible," reported The Coast News.

"It's not hard to make the connection that fish are getting tangled up in this, that we're turning the beaches into plastic sand; that there's a coral reef habitat in the middle of the ocean; that there are deleterious consequences of our trash," he said.

Adding to the growing collection of garbage that is swirling in the Pacific, scientists estimate that up to 20 million tons of debris from Japan's tsunami this year is making its way east toward Hawaii.

Be sure to check out these photos of an expedition to the North Atlantic Garbage Patch.

For more information about "Plastic Ocean," on sale October 27, visit the book's website.

Quotes, images and captions reprinted from "Plastic Ocean" by Capt. Charles Moore by arrangement with Avery Books, a member of Penguin Group (USA) Inc., Copyright ? 2011 by Capt. Charles Moore.

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Baby sea turtle, on its way out to sea, navigating plastic at Kamilo Beach, 2009

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Source: http://www.huffingtonpost.com/2011/10/26/plastic-ocean-pacific-conservation_n_1032897.html

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Friday 28 October 2011

Mummy Has Oldest Case of Prostate Cancer in Ancient Egypt

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Source: http://www.labspaces.net/114660/Mummy_Has_Oldest_Case_of_Prostate_Cancer_in_Ancient_Egypt

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Thursday 27 October 2011

U.S. and North Korea talks to resume after delay (reuters)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

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Glaciers in southwest China feel the brunt of climate change

Wednesday, October 26, 2011

Significant increases in annual temperatures are having a devastating affect on glaciers in the mountainous regions of south-western China, potentially affecting natural habitats, tourism and wider economic development.

In a study published today, 25 October 2011, in IOP Publishing's Environmental Research Letters, scientists examined data from 111 weather stations across south-western China and have shown that temperature patterns were consistent with warming, at a statistically significant level, between 1961 and 2008.

Of the 111 stations examined, 77 per cent displayed statistically significant increases in annual temperature.

Collating a broad range of research on glaciers during this time period, the researchers, from the Chinese Academy of Sciences, identified three characteristics that were consistent with the increasing trend in temperature; drastic retreats were observed in the glacial regions, along with large losses of mass and an increase in the area of glacial lakes.

In the Pengqu basin of the Himalayas, for example, the 999 glaciers had a combined area loss of 131 km2 between 1970 and 2001, whilst the Yalong glacier in the Gangrigabu Mountains retreated over 1500 meters from 1980 to 2001.

The implications of these changes are far more serious than simply altering the landscape; glaciers are an integral part of thousands of ecosystems and play a crucial role in sustaining human populations.

Continued widespread melting of glaciers, caused by increasing temperatures, could potentially lead to floods, mudflows and rock falls, affecting traffic, tourism and wider economic development.

South-western China has 23,488 glaciers, covering an area of 29,523 km2 across the Himalayas and the Nyainqntanglha, Tanggula and Hengduan mountains.

As well as temperature, the researchers also investigated precipitation; however the results were less marked. Annual increasing precipitation is consistent with climate change and was observed in 53 per cent of the stations. A decrease in annual precipitation can also influence glacial retreat and this was observed in central regions of the Himalayas.

The lead author of this study, Dr Zongxing Li, said, "I think glacial loss is caused mainly by rises in temperature, especially in the high altitude regions. From the 14 weather stations above 4000 m, there was an annual mean temperature increase of 1.73 ?C from 1961 to 2008.

"It is imperative we determine the relationship between climate change and glacier variations, particularly the role of precipitation, as the consequences of glacial retreat are far reaching."

###

Institute of Physics: http://www.iop.org

Thanks to Institute of Physics for this article.

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Source: http://www.labspaces.net/114620/Glaciers_in_southwest_China_feel_the_brunt_of_climate_change

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Wednesday 26 October 2011

How Apple?s A5 Chip and iOS 5 Will Change Mobile Gaming

If the last two weeks of mainstream press coverage are to be believed, the only relevant features in Apple’s new iPhone 4S are?Siri, the phone’s remarkable digital assistant, and the new?8-megapixel camera, which delivers near point-and-shoot image quality to Apple’s mobile platform.
But there’s one other feature that’s largely been ignored, even though it too was [...]

Source: http://feedproxy.google.com/~r/GearFactor/~3/yktxCq4tFQk/

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Tuesday 25 October 2011

Mobile Nations 9: Grand Theft Mobile

Our podcast feed Download Directly Subscribe in iTunes Subscribe in Zune Kevin, Phil, Derek, Dan, and Rene talk Windows Phone from Mango to Tango (and Nokia!), BlackBerry DevCon and BBX superphones, Android’s Ice Cream Sandwich and Galaxy Nexus, webOS and the road ahead, and...

Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/2YWKGvwXNsY/

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Nevada GOP moves caucus back to February 4th, 2012

rnc-logoAfter all the?posturing?by states to hold their primaries and caucus early so that it can benefit Mitt Romney, Nevada has decided move its caucus date back to February 4th, from January 17th, 2012. If Nevada would have left their January caucus date, they would have lost delegates as a ?penalty? for violating GOP rules.

Some of the lower tiered GOP candidates like Michele ?Bachmann and Jon Huntsman had threatened to boycott the GOP caucus altogether because of Nevada shifting it?s date to early January. Cry baby Huntsman even ?boycotted? the last debate in Las Vegas because of it. Now, according to CNN, New Hampshire is happy.

?Nevada?s decision to reschedule to February 4 will now allow Secretary of State Bill Gardner to schedule our primary at a more appropriate time than would?ve been allowed with Nevada?s earlier date,? said New Hampshire Republican Committee Chairman Wayne MacDonald in a statement. ?The New Hampshire Primary is important not just as a long standing tradition, but as an opportunity for lesser-funded or lesser-known candidates to have the opportunity to be heard.?

The senile old codger Harry Reid couldn?t be reached for comment.

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Monday 24 October 2011

Arianna Huffington: Sunday Roundup

This week brought us the latest episode of a certain reality show in which semi-famous people compete not to get voted off by dancing around, falling down, and generally making fools of themselves. I'm talking, of course, about the GOP debate in Las Vegas, which featured an intense, Spanish-flavored tango performed by Mitt Romney and Rick Perry (Romney, with his firm grip on Perry's shoulder, was clearly doing the leading). Elsewhere, in landscapes as disparate as Zanesville, Ohio and Sirte, Libya, armed gunmen hunted down and killed their prey -- the wild beasts on the run from the Muskingum County Animal Farm generating far more sympathy than the deposed (and despised) former dictator, whose death did nothing to answer the vexing question of how to actually spell his name, leaving obit writers everywhere to choose between Gaddafi, Qaddafi, Kadafi, Gadhafi, Gadafy, and the Man with the Golden Gun.

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Follow Arianna Huffington on Twitter: www.twitter.com/ariannahuff

Source: http://www.huffingtonpost.com/arianna-huffington/sunday-roundup_203_b_1026367.html

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Sunday 23 October 2011

No deal yet on euro crisis as the danger grows (AP)

BRUSSELS ? European leaders yet again put off the tough decisions needed to save the continent from its debt crisis but promised Sunday that a comprehensive plan is still coming.

As they dawdled, the danger was rising in an already high-stakes game.

Leaders of the continent's richest countries had unusually stern words Sunday for Italian Prime Minister Silvio Berlusconi, because many fear his nation could be the next dragged into the debt crisis if it does not make major budget cuts quickly.

That would spell disaster: Europe has rescued three small nations ? Greece, Ireland and Portugal ? but cannot afford to rescue Italy, the eurozone's third largest economy. Analysts say EU leaders, known as the European Council when they meet in Brussels, have to act now to eliminate the possibility of Italy's financial collapse.

"Between now and Wednesday, some members of the European Council have to convince colleagues that their country implements commitments fully," EU President Herman Van Rompuy said after the day's meetings, clearly referring to Italy. On Wednesday, leaders will gather again ? to unveil their solution, they promise.

When asked later what would happen if countries failed to fall in line, he responded: "They will make commitments."

Whether that message was getting through, however, was unclear. "The Italian fundamentals are very solid," Berlusconi told reporters after the 12-hour meeting.

For weeks it's been clear what the 17 countries that use the euro must do: reduce Greece's debt burden so the country eventually can stand on its own, force banks to raise more money so they can ride out the financial storm that will entail, and show that their European bailout fund is big and nimble enough to prevent larger economies from getting dragged into the crisis.

On Saturday, officials said the leaders were nearing agreement on slashing Greece's debts and strengthening the continent's banks, many of which are awash in Greek bonds.

But Sunday, the only solid detail to emerge from three days of intense talks was that banks will have to raise their capital buffers much faster than they had planned ? by the end of 2012, instead of 2019.

A European official said Saturday the banks would be forced to raise just over euro100 billion ($140 billion) more for their rainy-day funds, but leaders have not given an official figure.

Instead, at a series of news conferences Sunday, all they could do was promise to deliver big at their next summit.

"There are still problems to solve, but we are moving forward on all subjects," French President Nicolas Sarkozy said as he left Sunday's meetings. "There is a still a lot of work to do ... but there are no more blockages."

Analysts who have seen this pattern for months couldn't help but be skeptical.

"By failing to agree on anything substantial today, EU leaders may have set themselves up for an even bigger fall," said Sony Kapoor, managing director of the Re-Define think tank. "They owe it to Europe to pull a rabbit out of the hat now, but this seems to be beyond them."

Part of the challenge is that European leaders are unable to decide on anything until everything is in place, since each piece of the puzzle affects the others. The value of Greece's bonds can't be slashed until banks are strengthened ? or at least have confidence they can get help from the rescue fund. But some countries are reluctant to strengthen the fund until they know there's a plan to bring Greek debt under control.

Banks ? which have already agreed to take losses on their Greek bonds of some 21 percent ? are already rumbling at suggestions that they might need to double or nearly triple that figure. But without reducing Greece's debt load, the whole plan does not work.

The eurozone also still needs to work out how to most effectively use Europe's bailout fund to make sure Italy and Spain don't see their borrowing costs spiral out of control, as happened with Greece, Portugal and Ireland.

Officials said leaders had reduced seven different proposals down to two options, which are not mutually exclusive. Both options would essentially use the European Financial Stability Facility to insure investors against a first round of losses on bonds from wobbly countries.

But before that can be done, those countries have to convince their partners in the eurozone that their weakness is only temporary and they can get back into shape soon.

German Chancellor Angela Merkel and France's Sarkozy came out with particularly strong words for Italy.

"We made it very clear that Italy is a big and important partner for the euro area and that everything needs to be done to live up to this responsibility," Merkel told reporters after the two met with Berlusconi.

"Trust does not just come from a firewall," she added. "Italy has great economic power but Italy also has a very high overall debt level. And that was to be taken down in the coming years in a credible way."

The stern tone reflected the seriousness of Europe's problems, which have roiled financial markets in recent months and been blamed for slowing economic growth across the globe.

Worst off, of course, is Greece, which is reeling from repeated rounds of budget cuts, job cuts and new taxes that have sparked near-daily strikes and even riots. The country is looking at a fourth year of recession and unemployment has hit a record of 16.5 percent.

"Greece has proven again and again that we are making the necessary decisions to make our economy sustainable," Greek Prime Minister George Papandreou told reporters Sunday. "But it's been proven now that the crisis is not a Greek crisis. The crisis is a European crisis, so now is the time that we as Europeans need to act."

To ease the pressure, banks will be asked to accept much bigger losses on Greek bonds.

Austria's chancellor said the cut in the value of Greek government bonds will likely be raised "in the direction of 40 to 50 percent."

"A cut in the debt is the right step," Werner Faymann told the Austrian newspaper Wiener Kurier.

Despite massive budget cuts and reforms, a new report says Greece's economic situation is still dire and it could take the country decades to emerge from the crisis.

The eurozone has accepted that it will have to provide Greece with tens of billions of euros in extra aid ? on top of euro110 billion ($152 billion) granted in May 2010. But to keep a lid on that amount, banks must go far beyond a preliminary deal reached in July, in which they promised take a cut of 21 percent of their Greek bondholdings.

The near-consensus among eurozone countries that Greece's debt will have to be slashed is one of the reasons banks across Europe ? not only in the 17-country eurozone ? will be forced to shore up their capital buffers in the coming months.

To that end, Sarkozy said the EU will require banks to raise their capital buffers to higher levels by 2012 rather than the 2019 laid out under the Basel III banking rules.

___

Gabriele Steinhauser, Raf Casert, Slobodan Lekic, Don Melvin and Elena Becatoros contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/ap/20111023/ap_on_bi_ge/eu_europe_financial_crisis

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No-Cupcakes School Policy Battles Childhood Obesity (ContributorNetwork)

Northeast Elementary Magnet School, in Danville, Ill., won a gold medal for fighting childhood obesity with a "no cupcakes" policy, active learning, classroom fitness and improved school nutrition. Northeast is the first elementary school to win the Alliance for a Healthier Generation award. Here's a look at AHG, Northeast's anti-obesity initiatives and how parents are responding.

What is the Alliance for a Healthier Generation?

AHG is a partnership between the American Heart Association and the William J. Clinton Foundation. It connects with health care professionals, community resources, television foodies, diet gurus, as well as school. AHG has lots of big names onboard: Jillian Michaels, Rachel Ray, Top Chef winners and former President Bill Clinton. AHG awards health initiatives that fight childhood obesity.

Why are schools rethinking health issues?

Thirty percent of children, ages 2-19, in the U.S. are overweight and 17 percent are obese. This rate has tripled over the last 30 years. BMI, or Body Mass Index (weight-to-height ratio) is calculated differently in children than with adults. A child's BMI is compared to national developmental averages or growth percentiles. What percentile a child's BMI puts him in depends upon age and gender. Generally, a BMI over 25-27 is considered overweight. Childhood obesity is most prevalent among low-income families, who lack access to healthier foods. Children in rougher areas often cannot safely walk to school or play outside, and so do not get enough exercise.

What changes has Northeast Elementary made in its school meal menus?

There is a zero-tolerance policy for junk food, candy and soda pop. Parent's may not send sweet treats for birthdays or classroom parties. Breakfasts feature low-sugar cereals and entrees. Low-fat plain white milk is the beverage of choice. There are plenty of fresh vegetable options. Lunch menus serve fresh fruit as a dessert. Northeast has dropped fried foods from the menu. Children are taught how to read nutrition data charts and choose more nutritious foods.

What about fitness initiatives?

Students exercise every day. They are actively engaged in lessons, and don't just sit passively doing sedentary activities. Teachers wear pedometers. This helps kids see how easy it is to burn calories just in daily activities. It makes exercise seem more doable and enjoyable.

Is it just physical health that Northeast is concerned with?

No. Emotional well-being is one of Northeast's goals, too. The school teaches positive self-image and healthy attitudes toward food. Sweet treats aren't used as rewards or withheld as punishment. Children report liking Northeast's proactive emphasis. They take pride in their school's healthy approach. Northeast also encourages healthy eating as a way to improve learning, retention, even attendance. Obese kids tend to have other health problems and miss more school than peers of normal weight.

How do parents feel about the "no sweets" changes?

Republican vice-presidential hopeful and tea partier, Sarah Palin, may not like being told what to send for birthday treats and classroom parties. Last year, Palin decried a Pennsylvania school's "no cookie/sweets" policy. Palin said she would bake cookies to prove that these policies represent "a nanny state run amok." That was at a wealthy private school.

Parents at Northeast, located in a blue-collar, working-class neighborhood, see it a little differently. If enrollment numbers are any indication, parents appreciate the school's healthy lifestyles focus. Despite its humble location, Northeast is over-booked for kindergarten next year: 80 applicants are vying for 48 slots.

Marilisa Kinney Sachteleben writes about parenting issues from 23 years raising four children and 25 years teaching K-8, special needs, adult education and homeschool.

Source: http://us.rd.yahoo.com/dailynews/rss/parenting/*http%3A//news.yahoo.com/s/ac/20111020/hl_ac/10250331_nocupcakes_school_policy_battles_childhood_obesity

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Saturday 22 October 2011

Old-time radio convention meets for last time

Writer and director Edgar Farr Russell III, left, directs Russell Horton, standing center, as Jughead Jones, and others during rehearsal of his "Radio Goes To War," episode, "Any Bonds Today" at the Friends of Old-Time Radio convention in Newark, N.J., Friday, Oct. 21, 2011. To devotees of old-time radio, Fibber McGee is still opening that closet and Fred Allen and Jack Benny are still enjoying their feud. But time has run out on this convention. This weekend's gathering of the Friends of Old-time Radio is the 36th and last, says the organizer. (AP Photo/Mel Evans)

Writer and director Edgar Farr Russell III, left, directs Russell Horton, standing center, as Jughead Jones, and others during rehearsal of his "Radio Goes To War," episode, "Any Bonds Today" at the Friends of Old-Time Radio convention in Newark, N.J., Friday, Oct. 21, 2011. To devotees of old-time radio, Fibber McGee is still opening that closet and Fred Allen and Jack Benny are still enjoying their feud. But time has run out on this convention. This weekend's gathering of the Friends of Old-time Radio is the 36th and last, says the organizer. (AP Photo/Mel Evans)

A book about The Shadow radio series sits nearby as Lauri Bortz, dressed in a 1940's outfit, looks through bins of old radio programs at the Friends of Old-Time Radio convention in Newark, N.J., Friday, Oct. 21, 2011. To devotees of old-time radio, Fibber McGee is still opening that closet and Fred Allen and Jack Benny are still enjoying their feud. But time has run out on this convention. This weekend's gathering of the Friends of Old-time Radio is the 36th and last, says the organizer. (AP Photo/Mel Evans)

Lauri Bortz is dressed in a 1940's outfit as she looks through bins of old radio programs and movies at the Friends of Old-Time Radio convention in Newark, N.J., Friday, Oct. 21, 2011. To devotees of old-time radio, Fibber McGee is still opening that closet and Fred Allen and Jack Benny are still enjoying their feud. But time has run out on this convention. This weekend's gathering of the Friends of Old-time Radio is the 36th and last, says the organizer. (AP Photo/Mel Evans)

Writer and director Edgar Farr Russell III, left, directs Russell Horton, standing center, as Jughead Jones, and others during rehearsal of his "Radio Goes To War," episode, "Any Bonds Today" at the Friends of Old-Time Radio convention in Newark, N.J., Friday, Oct. 21, 2011. To devotees of old-time radio, Fibber McGee is still opening that closet and Fred Allen and Jack Benny are still enjoying their feud. But time has run out on this convention. This weekend's gathering of the Friends of Old-time Radio is the 36th and last, says the organizer. (AP Photo/Mel Evans)

(AP) ? For one weekend a year, the ghosts and survivors of Jack Benny, Benny Goodman, Goodman Ace and hundreds of other legends of the old days of radio hold court at a hotel across the road from Newark Airport.

The annual Friends of Old-Time Radio Convention has been meeting for 36 years. But when it signs off Saturday night, it will be for the last time. The reason is simple, says Jay Hickerson, a musician who has been running the show from the beginning: the march of time.

"Lack of OTR (old-time radio) guests. And the committee is getting older," he said.

The gathering, humble as it is, used to be able to call on a constellation of stars from the early days of radio.

Now it's down to former child stars in their 80s and 90s. Arthur Anderson, 88, who acted as a teenager with Orson Welles, is an honored guest. Grandsons of 1930s song and dance star Eddie Cantor and Brace Beemer, the voice of the Lone Ranger for most of its run on radio, are on the program.

Collecting old-time radio shows and trivia has never been a young person's game. But most of the convention-goers are too young to have firsthand recollections of the shows they're buying, recreating and discussing on panels.

Gary Yoggy, 73, has been to all 36 of the conventions.

"It's my favorite weekend of the year. It tops Christmas," he said.

Yoggy, a retired history teacher from Corning, N.Y., is part of the committee that puts on the convention. He directed a re-creation of a Tom Mix episode for a Friday afternoon program.

"It's like reliving my youth," he said. "I was a kid when the golden age of radio was beginning to die."

Simon Jones is one of the celebrity guests for the weekend. Jones doesn't exactly qualify as a Golden Age of Radio star. He played Arthur Dent in the BBC's hugely popular radio and TV adaptations of The Hitchhiker's Guide to the Galaxy, starting in 1978. But he's been here before and is delighted to be asked.

"I've learned quite a lot about what went on before me," he said.

Listeners who started as children, he said, make the most loyal fans. "If you can catch them that young, maybe they'll become addicted later on."

But it's not just the radio programs that bring participants back year after year.

Stuart Weiss has been part of the steering committee from the beginning. He moderates a music panel with Brian Gari, the Cantor grandson. Weiss likens the gathering to a family reunion.

"These are old friendships. But you don't keep in touch during the year. We come here, it's as if we were together yesterday," he said.

Weiss, a party supply salesman from Staten Island, was inspired by the convention to start his own radio show on the Internet. It's eight hours long.

"I can't stop," he said. The party supply business isn't doing too well these days, but "when I do my show, I forget all my problems. And for eight hours, I'm in heaven."

Sometimes the family aspect is literal. Gary Yoggy met his wife at the convention. They've been married 29 years. Jeff Muller, 45, has been coming since he was a teenager. He brings his father.

"I guess it's his second childhood, in a way," he said.

And when the curtain comes down, after Jay Hickerson and his wife Karen play "I'll Be Seeing You" and a version of "Thanks for the Memories," with special lyrics written for the convention?

Weiss joked he'll come back to the Newark Airport Ramada anyway and wander around empty rooms. Yoggy said he wants to help revive radio drama, which withered away decades ago, in the United States at least.

Jones, the Hitchhiker's Guide star, said the form remains alive in Britain. Next year, the radio version goes on a live tour.

"Obviously, this art form hasn't quite died," he said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2011-10-21-Old-Time%20Radio-Signing%20Off/id-bf1d667060cc49dabbcd778efcdd88a8

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Christina Aguilera's Skimpy Shopping (omg!)

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Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/http___omg_yahoo_com_photos5308/43345844/*http%3A//omg.yahoo.com/photos/christina-aguileras-skimpy-shopping/5308

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Friday 21 October 2011

Rate on 30-year fixed mortgage falls to 4.11 pct. (AP)

WASHINGTON ? The average rate on the 30-year fixed mortgage was nearly unchanged this week after rising sharply last week.

Freddie Mac said Thursday that the rate on the 30-year loan edged down to 4.11 percent from 4.12 percent last week. The week before, it fell to 3.94 percent. That's the lowest rate ever, according to the National Bureau of Economic Research.

The average rate on the 15-year fixed mortgage ticked up to 3.38 percent from 3.37 percent. It hit a record-low of 3.26 percent two weeks ago.

Low rates have done little to revive the lagging housing market, which has struggled with weak sales and declining prices. Many can't qualify for loans because their credit is weak or they can't afford a down-payment. Most of those who can afford to refinance already have.

The number of Americans who bought previously occupied homes fell in September and is on pace to match last year's dismal figures ? the worst in 13 years.

The National Association of Realtors said Thursday that home sales fell 3 percent last month to a seasonally adjusted annual rate of 4.91 million homes. That's below the 6 million that economists say is consistent with a healthy housing market.

Sales of new homes are on pace to finish the year as the lowest on records dating back a half-century. Prices have been sliding because the market is flooded with houses being sold in foreclosure.

Many borrowers are unable to take advantage of the low rates because they can't meet banks' restrictive lending standards, or are unable to scrape together a down payment.

The low rates have caused a modest boom in refinancing, but that benefit might be wearing off. Most people who can afford to refinance have already locked in rates below 5 percent.

There have been a few modest signs of life for housing. Homebuilders started projects in September at the fastest pace in 17 months, the government said Wednesday. Most of the gain was driven by a surge in volatile apartment construction.

Still, single-family home construction, which represents nearly 70 percent of the market, increased only slightly. And building permits, a gauge of future construction, fell.

The Federal Reserve has been trying to reduce long-term rates by buying longer-dated Treasurys. Mortgage rates tend to track the yield on the 10-year Treasury note. Buying by the Fed pulls the yield lower.

The average rate on a 30-year fixed mortgage fell below 4 percent for the first time in history this month, just as the 10-year yield hit its own record low. Rates have edged up since then.

Rates have been below 5 percent for all but two weeks in the past year. Just five years ago they were closer to 6.5 percent.

The low rates being offered don't include extra fees, known as points, which many borrowers must pay to get the lowest rates. One point equals 1 percent of the loan amount. The average fees for the 30-year and 15-year loans were unchanged at 0.8 point.

To calculate average mortgage rates, Freddie Mac surveys lenders across the country Monday through Wednesday of each week.

The average rate on a five-year adjustable-rate mortgage fell to 3.01 percent from 3.06 percent. It hit a record-low of 2.96 percent two weeks ago.

The average rate for the one-year adjustable-rate mortgage rose to 2.94 percent from 2.90 percent. It fell last month to 2.81 percent, the lowest on records dating back to 1984.

The average fees on the one-year and five-year loan were unchanged at 0.6 point.

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/ap/20111020/ap_on_bi_ge/us_mortgage_rates

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Thursday 20 October 2011

[OOC] The Royalty Survival Games

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World Solar Challenge Automotive Race Kicks Off in - Inhabitat

Fastest solar car, solar race, solar car technology, World solar race, solar car Australia, solar car race leader,solar car, solar power car race, world solar challenge, World Solar Challenge Competition

37 teams from all over the world are making a go at this year?s World Solar Challenge, by?traversing continental Australia in a solar vehicle.?Teams need to cross 3,000 km of desert, from Darwin to Adelaide, in a single shot, relying on the sun for almost all the energy needed to make the journey. Rain and smoky conditions are making the race a real challenge by adding a layer complexity to the largest?solar car race in the world, but now?on day two, Tokai University (who won in 2009) is making headway with a speedster that can top out at 160 kmh. University of Michigan and the Dutch Nuon Solar Team are also hot contenders in this extraordinary test of engineering and resolve.

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This is the 11th biannual race, which first got its start in 1987. Each team is allowed to charge their batteries to 5kW, and then are to only use the sun or regenerative breaking to make the rest of the trip. Teams begin at the same time and race until 5pm when they make camp right on the side of the road.

Many are admittedly not much more than a platform for solar panels supported by a tripod wheels and a translucent bump for the driver. And besides cleaning the car and keeping tires inflated, the cars are not to be serviced. Most vehicles have the drivers board below the raised solar ?hood? and slip into a cockpit. (Good luck if they need to scratch their nose!)?The driving can be tricky too ? the lightweight carbon fiber bodies can be blown around in a wind or tip when taking a sharp corner.

Cars ?bank? the energy that they don?t need during midday for application in the morning and during last stretch of the day. The technology is impressive, especially when considering that the cars can cruise at 90 km per hour running only on sunshine that is only 1,366 watts per square meter.

Now considering all the inefficiencies of converting to electricity and mechanical energy, the promise of solar power still has a lot left to be exploited.

+ 2011 World Solar Challenge

Source: http://inhabitat.com/world-solar-challenge-automotive-race-kicks-off-in-australia/

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Tuesday 18 October 2011

Dan Morain: A new general in marriage war (Sacramento Bee)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/149042819?client_source=feed&format=rss

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Genomic sequence and comparison of two macaques reveal new insights into biomedical research

ScienceDaily (Oct. 17, 2011) ? The South China Center for Innovative Pharmaceuticals, Sun Yat-Sen University, and BGI, the world's largest genomic organization, announced that they were among the research organizations from China, US and UK comprising an international research group that completed the genome sequence and comparison of two non-human primate animal models -- Chinese rhesus macaque and cynomolgus.

The study is published October 17 online in the journal Nature Biotechnology.

This study marks an important milestone in macaque genome research and plays an important role in the better understanding of genetic differences among macaque monkeys. It also reveals new insights into the evolutionary history of the macaque genome, human disease research and drug discovery. "We believe these insights will generate great interest among geneticists, medical scientists and clinical researchers worldwide and facilitate the effective use of non-human primate models in medical research." said Prof. Guangmei Yan, the co-leading author of the study and Senior Consultant of The South China Center for Innovative Pharmaceuticals.

Macaques are the most extensively used non-human primates in biomedical research. They have contributed to pre-clinical studies all over the world, including the discovery of vaccines, drug development and behavioral research. Indian rhesus macaque, in particular, has been used for more than half century in pre-clinical research. However, India banned the export of all macaques in 1978, leading to the current shortage of resource for pre-clinical research.

Facing this problem, scientists have been gradually paying more attention on other macaque species/subspecies for a suitable alternative animal model, particularly on the Chinese rhesus macaque (Macaca mulatta lasiota) and the cynomolgus/crab-eating macaque (Macaca fascicularis). "In order to select the most relevant non-human primate model in a study, it is important for researchers to understand the genetic variation and inter-species differences among macaque species as well as the genetic diversity between macaques and human." said Dr. Guojie Zhang, the co-leading author of the study and Director of Genomic Evolution and Comparison Centre at BGI..

In this study, the team sequenced the genomes of a female Chinese rhesus macaque (CR) and a female cynomolgus (CE) by the whole-genome shotgun strategy on BGI's next-generations sequencing platform. The genome size of CR and CE is about 2.84 Gb and 2.85 Gb, respectively. Using the genomic data, the researchers also compared the two genomes with the previously sequenced Indian rhesus macaque (IR) and explored the abundant genetic heterogeneity among the three macaques. They found there were over 20 million single-nucleotide differences and 740,827 indel events in the three macaque species, which will provide abundant genetic heterogeneity for use in future biomedical analysis and application. It is important to note that a large number of genetic differences were shared between at least two macaques. The divergence rate of CE/IR (40%) was higher than that of CR/IR (31%) and CR/CE (34%).

In addition, the divergence pattern between CR, CE and IR also suggested the occurrence of ancient introgression from CR to CE over an extended period of evolutionary time. 217 strong selective sweep regions were identified with reduced variability between the three macaque species, implying that some genes in macaques may experience positive selection in evolution. "Genome sequence and comparison of CR and CE confirmed that introgressive hybridization probably played an important role in the formation of the genome of the extant mainland-origin cynomolgus macaque. Thus, the CE could be a useful model for exploring gene interchanges between primate species, and the consequent role of this process in primate evolution and speciation." added Dr. Zhang

Another interesting finding is that some specific genes in macaques display a high degree of sequence similarity with human disease gene orthologues and drug targets. This demonstrated the prominent use of macaques in biomedical research. To study the orthologues of human druggable protein domains in macaques and to create a resource for the therapeutic exploitation of the 'druggable genome'; the team screened the macaque orthologues for currently known drug domains. Almost all of the druggable orthologues can be detected in the three-macaque species/subspecies, indicating that these animal models are likely to be functionally equivalent. However, in very few cases, macaques exhibit differences with respect to human.

"We are excited about all the findings in the study, especially those with great biomedical interests. For instance, macaques have protective immunity against human retrovirus, HIV-1 virus, but are easily infected by SIV virus. TRIM5? protein in macaques can lead to anti-infection of HIV-1, whereas TRIM5? in human does not have the same effect. Variations of TRIM5, a gene encoding TRIM5? were observed at different frequency in the macaque population, and this may be the key hereditary factor for the ability to protect against HIV-1 infection among individual macaques." added Dr. Zhang.

Adding to the efforts in the genomic studies of macaques, earlier this month BGI has released the first monkey exome sequencing platform based on next-generation sequencing technology and the monkey exome capturing array (MECA). MECA is a proprietary exome capture array designed by BGI for capturing the entire monkey exome. The combination of this revolutionary array and BGI's high-throughput sequencing technology not only can simplify the workflow of exome sequencing experiments, but also improve cost-effectiveness and turnaround time.

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Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Beijing Genomics Institute, via EurekAlert!, a service of AAAS.

Journal Reference:

  1. Guangmei Yan, Guojie Zhang, Xiaodong Fang, Yanfeng Zhang, Cai Li, Fei Ling, David N Cooper, Qiye Li, Yan Li, Alain J van Gool, Hongli Du, Jiesi Chen, Ronghua Chen, Pei Zhang, Zhiyong Huang, John R Thompson, Yuhuan Meng, Yinqi Bai, Jufang Wang, Min Zhuo, Tao Wang, Ying Huang, Liqiong Wei, Jianwen Li, Zhiwen Wang, Haofu Hu, Pengcheng Yang, Liang Le, Peter D Stenson, Bo Li, Xiaoming Liu, Edward V Ball, Na An, Quanfei Huang, Yong Zhang, Wei Fan, Xiuqing Zhang, Yingrui Li, Wen Wang, Michael G Katze, Bing Su, Rasmus Nielsen, Huanming Yang, Jun Wang, Xiaoning Wang, Jian Wang. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Nature Biotechnology, 2011; DOI: 10.1038/nbt.1992

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2011/10/111017102553.htm

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Monday 17 October 2011

Genetic Profiling Adds New Dimension to Breast Cancer Treatment (HealthDay)

FRIDAY, Oct. 14 (HealthDay News) -- Treatment for breast cancer has advanced in recent years by becoming more and more personalized.

Not personalized to the patient, mind you, but to the particular tumors and cancer cells inside that patient.

New tests are allowing doctors to figure out what genetic or biological factors are driving each individual woman's type of cancer, and new therapies are being targeted to directly attack those specific factors.

"When it comes to treating breast cancer, we used to throw the book at everyone," said Dr. Christy A. Russell, a board member of the American Cancer Society's California division and an associate professor at the University of Southern California Keck School of Medicine. "Now it's much more targeted."

That's a message worth sharing during October, Breast Cancer Awareness Month.

The same five treatment options are still available to women with breast cancer: surgery, chemotherapy, radiation therapy, hormone therapy and targeted therapy. But researchers are honing and improving each option, either to better target the cancer cells or to provide women with a wider range of treatment choices.

"Within each of those types of treatment modalities, we are refining how the treatment is delivered or how we choose which treatment is appropriate for each patient," said Susan Brown, a registered nurse and director of health education for Susan G. Komen for the Cure, a nonprofit group focused on fighting breast cancer.

For example, there have been few advances in creating new chemotherapy drugs to battle breast cancer, Russell said. "What has changed is trying to figure out who will benefit from chemotherapy," she said. "We are taking the cancers and having them evaluated genetically, to give us some genetic signatures to tell us if those cancers would shrink if they got chemotherapy."

This "genomic profiling" of a woman's specific cancer has "reduced the number of women with early breast cancer who are having to be treated with chemotherapy," Russell said.

One new test in particular, Oncotype DX, is being used to help women who would most likely benefit from hormone therapy because their cancer is spurred by estrogen or other female hormones.

Oncotype DX analyzes the genetic makeup of breast cancer cells to determine the likelihood that a woman's particular cancer will recur after hormone therapy treatment. If the likelihood is high, doctors will recommend that the woman undergo both hormone therapy and chemotherapy, Brown said.

"This information can help doctors decide whether to add chemotherapy to a treatment regimen that already includes hormone therapy," she said.

Doctors also have learned to analyze cancers for specific factors that, if blocked, can make chemotherapy more effective in killing the cancer cells.

About one-fourth of all breast cancer patients have cancer cells containing mutated forms of HER2neu, a gene that promotes the creation of a growth factor protein.

"In some breast cancers, instead of the cancer cells having two copies of the gene, the cells have 10 or 20 or more copies of the gene," Russell said. "The gene is producing a protein that causes the cell to grow much more rapidly and uncontrollably."

Treatment with a drug called trastuzumab (Herceptin) can block the growth signals transmitted by the gene, slowing the progress of the cancer and making it more susceptible to chemotherapy, Russell said.

"Most of the research going on now is trying to figure out how to combine these new targeted agents with chemotherapy so we can focus in on the specific gene abnormalities that are going on in the cells," she said.

This type of research also is combating the ability of cancer to grow resistant to chemotherapy and hormone therapy.

Researchers have learned that a growth factor protein known as mTOR promotes the spread of cancer cells and can bolster their resistance to hormone therapy, Russell said.

"Medications that act as mTOR inhibitors appear to be able to make some cancer cells that have become resistant to hormone therapy become sensitive to the therapy again," Russell said. "There are many pathways we are aware of that cancer cells are able [to use] to overcome their ability to be killed by chemotherapy. All of these different gene pathways are becoming known, and, as they are becoming known, they are developing drugs that are targeting those pathways. That's where the majority of the clinical trials are occurring."

Which means it is essential for women with breast cancer to participate in clinical trials, Brown said.

"Currently, fewer than 5 percent of patients enroll in clinical trials," she said. "The only way we're going to know more is if we are able to translate what we think we've learned in a lab into a clinical situation," Brown explained.

"Everything we know about breast cancer now is because of the very courageous women who came before us and enrolled in clinical trials," Brown added.

More information

The American Cancer Society has a detailed guide to breast cancer.

A companion article describes one woman's account of how breast cancer changed her life.

Source: http://us.rd.yahoo.com/dailynews/rss/health/*http%3A//news.yahoo.com/s/hsn/20111015/hl_hsn/geneticprofilingaddsnewdimensiontobreastcancertreatment

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